Andy Ham has been ruled out for the rest of the season, casting doubts on his future at the Hammers.
It is known that the future, who featured nine times for England between 2010 and 2012, wants to face an extended spell on the sidelines after undergoing an operation on his ankle.
Carroll has his current contract expiring at the end of the season.
The operation may prove to be a factor in Manuel Pellegrini's decision on whether to keep the 30-year-old.
West Ham has the option of extending his contract by an extra two years, but has given the latest setback, that now appears unlikely.
In what has been a blemished season injury, Carroll has featured only 14 times for the Hammers, scoring just one goal, that's coming in the win over Birmingham in the FA Cup.
Carroll last featured for West Ham at the 1-0 defeat at Manchester City back in February, where he played the full 90 minutes.
Carroll missed the first half of the season with an ankle injury after undergoing an operation, and there are fears that the current setback is a re-occurrence of the same injury sustained in pre-season.
The future signed for West Ham on a six-year contract in 2013, after initially impressing on loan from Liverpool, where he netted seven times in 24 appearances.
However, Carroll's West Ham career, which has 34 goals in 142 games, may be coming to an end.
The Reds signed Carroll for £ 35 million pounds in 2011, which at the time was the highest amount paid for a British footballer, but less than two years later.