Four new coronavirus cases have been confirmed in Wales, bringing the total to 19.
It includes a patient who has no travel history in a country where the virus circulates and who is not known to have had contact with another confirmed case.
Frank Atherton, Chief Medical Officer for Wales, said that three of the new cases have returned to Wales from northern Italy.
Two of these are residents of the Powys area and the other lives in Swansea.
The other new case, residing in the Caerphilly area, has no precedent for travel to a country where the virus circulates, so it is probably the first incidence of “community spread” of the virus in Wales.
Dr Atherton said: “I can confirm that four other people in Wales tested positive for coronavirus (COVID-19), bringing the total number of positive cases in Wales to 19.
“All individuals are managed in clinically appropriate settings. All appropriate measures have been taken to provide assistance to individuals and to reduce the risk of transmission to others.
“We have always been clear that we expected the number of positive cases to increase, in line with what happened in other parts of the world.
“I would like to take this opportunity to assure the public that Wales and the whole of the UK are prepared for this type of incident. By working with our partners in Wales and the UK, we have implemented our planned response, with solid control infection measures in place to protect public health. “
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The announcement follows the news that an employee of the Newport Office for National Statistics has been diagnosed with Covid-19.
On Tuesday, a worker at the call center for Sky in Cardiff was also hit by the virus and is self-insulating.
Coronavirus has flu-like symptoms including fever, cough or breathing difficulties. Current evidence indicates that most cases appear to be mild.
As of Friday March 6, 634 people in Wales have been tested for the new coronavirus (COVID-19).
Health Minister Vaughan Gething, speaking on Wednesday to Senedd, said 11 drive-thru coronavirus test centers have been established across the country.
However, Plaid health spokesman Cymru Rhun ap Iorwerth warned that there was not enough capacity in the intensive care units in Wales to cope with an influx of coronavirus patients.