Six people suffering from morbid obesity have agreed to let doctors care to plant a flea in their brain that zaps them when they are thirsty for food.
Scientists at Stanford University want to know if giving electric shocks could help people with "loss of nutritional control".
The clinical trial will last five years and each participant will carry the chip for 18 months at a time.
The chip will monitor brain activity for six months in order to identify the type of activity leading to binge eating.
After six months, the zap will be triggered, giving people a slight electric shock each time they think they reach the cabinets.
Other chips could be deployed if the procedure turns out safe and effective.
However, scientists have pointed out that this product is not intended for people who are trying to lose a little weight and is only suitable for people "dying of obesity".
In order to participate in the study, individuals must have a body mass index over 45 years old and not lose weight due to gastric bypass surgery or cognitive behavioral therapy.
A healthy BMI is between 18.5 and 24.9, and anything above 27.5 is considered high risk.
The study will focus on an area of the brain called the nucleus accumbens – the pleasure center of the brain, which deals with feelings of reward and dependence.
However, scientists have admitted that it would be difficult to separate the brain's response to fatty foods from that of healthy foods.
It is also feared that the stimulation causes feelings of depression or anhedonia – a loss of interest