Houston vs Colorado Prediction, Picks & Odds | 13 Nov 2026

The college football landscape features a high-stakes Big 12 clash on Friday, November 13, 2026, as the No. 14 Houston Cougars (7-2) hit the road to take on the Colorado Buffaloes (3-6) at Folsom Field, according to SportsTalk 790. Doc's Sports notes that the matchup takes place in Boulder, Colorado. Pre-match discussion among wagering markets and analysts has focused heavily on point spreads, game totals, and individual player props.

Recent form guides indicate contrasting trajectories for the two programs as they head into Friday night. According to Sportsgambler, Houston secured a home win in their previous outing, defeating the Cincinnati Bearcats 31-24 at TDECU Stadium. Meanwhile, the Colorado Buffaloes lost on the road in their last game, falling 20-10 against the Arizona State Sun Devils at Mountain America Stadium. Historical precedent also favors the visitors, as Houston previously defeated Colorado comfortably by a 36-20 scoreline at TDECU Stadium.

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Wagering markets have priced Houston as the betting favorites to land a victory, with Sportsgambler noting that the team is available at -312 to win. The current spread sits at 8.5, though some betting discussions highlight an attractive -9.5 line that could be covered. The total points line is established at 51.5. In terms of past performances, Colorado holds five wins and five losses in their last ten games at home, scoring an average of 25.70 points per matchup while conceding 26.30. On the other side, Houston enters the contest with an 8-2 mark in their past ten road games, putting up 30.20 points on average and giving up 21.00.

Individual player props have also attracted attention from tipsters. For Colorado, quarterback Isaac Wilson is priced at -114 to finish with fewer than 220.5 passing yards, a line analysts expect he may fall short of. Teammate Amare Thomas is priced at -114 to have less than 71.5 receiving yards, with predictions suggesting the total looks too high. Same-game parlay picks combine Houston on the spread, the over on 51.5 total points, and Isaac Wilson to go under his passing yards line, with alternate correct score picks pointing toward a potential 38-23 outcome.

Beyond the action on the gridiron in Boulder, college basketball scheduling adds to the busy sporting calendar on the same date. According to Bleacher Nation, the Texas State Bobcats (3-0) are set to extend a three-game winning streak when they host the Southern Miss Golden Eagles (2-1) on November 13, 2026, at Strahan Arena at the University Events Center. Texas State enters following a 72-65 home win over UT Rio Grande Valley on Tuesday, where Dimp Pernell scored a team-high 26 points. Southern Miss arrives after an 84-80 overtime win against Jackson State on Wednesday, led by Jalyke Gaines-Wyatt with 28 points. The opening tip for this basketball contest is scheduled at 8 p.m. ET.

Fans looking to follow the action live have multiple avenues available. Viewers can access college football coverage via streaming services such as Fubo, purchase officially licensed merchandise through Fanatics, or secure tickets through platforms including StubHub and Vivid Seats, as detailed by SportsTalk 790 and Bleacher Nation.

What to Watch Next

• Kickoff at Folsom Field for Houston versus Colorado on Friday, November 13, 2026.
• Live market odds updates, final team sheet confirmations, and injury tracking prior to match time.
• The opening tip between the Texas State Bobcats and Southern Miss Golden Eagles at 8 p.m. ET on November 13, 2026.
• Post-match analysis on how the Houston spread, total points, and Colorado player props ultimately settle.